Monday, May 18, 2020

Vaccine

Moderna’s coronavirus vaccine shows encouraging early results in human safety trial

...eight participants who received low and medium doses of Moderna’s vaccine had blood levels of virus-fighting antibodies that were similar or greater than those in patients who recovered. That would suggest, but doesn’t prove, that it triggers some level of immunity.
The U.S. is aiming to have hundreds of millions of doses of a vaccine broadly available by the end of the year.
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An effort led by the University of Oxford, in partnership with pharmaceutical giant AstraZeneca, plans to have millions of doses of vaccine available by fall.
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Vaccine experts have said that these accelerated development timelines are theoretically possible, but extremely optimistic — and depend on everything going right. They stress that it will be crucial to gather convincing data the vaccines are safe and effective before using them broadly — and the new data are promising but preliminary, from the earliest phase one trials that test safety in healthy people

“I would certainly take this as good news, and it’s certainly worth moving forward” into later stage trials, said Daniel Salmon, director of the Institute for Vaccine Safety at the Johns Hopkins Bloomberg School of Public Health. “There’s just historically, if you look at vaccine development, lots of vaccines that look good out of phase one that don’t turn out to be good products.”

The data released Monday by Moderna is encouraging, but represents only a first step in a long process to bring a vaccine to market. It comes from an interim report on dozens of patients followed over weeks, whereas vaccine approval requires broad testing in thousands of patients followed over many months or years.
https://www.washingtonpost.com/health/2020/05/18/coronavirus-vaccine-first-results/?itid=lk_inline_manual_6

Well, that's more like a strip show, exciting, teasing, than the real thing. I never liked strip shows.